Library · one definitive page per molecule
Peptide guides
Every guide separates three things marketing collapses into one: what the published evidence shows, what regulators have actually said, and what the math looks like. Where human data doesn't exist, the first paragraph says so.
Foundations
How peptide reconstitution works
The concentration math, bacteriostatic water, storage, and the conversion errors the FDA has documented.
Molecule guide · skin & repair
GHK-Cu (Copper Peptide)
What GHK-Cu actually does: topical evidence, injectable unknowns, the legal line between the two, dosage math, and the blue authenticity test.
Molecule guide · inflammation
KPV Peptide
KPV exploded in gut-health circles. What the alpha-MSH fragment is, what preclinical research shows, the missing human data, and the dosage math.
Molecule guide · sexual health
PT-141 (Bremelanotide)
PT-141 has an FDA-approved twin: Vyleesi. What the approval covers, what the gray market sells, blood-pressure warnings, and the vial math.
Molecule guide · recovery
BPC-157
BPC-157 honestly reviewed: rodent data vs zero human trials, FDA Category 2 status, WADA prohibition, reported side effects, and dosage math.
Molecule guide · metabolism
MOTS-c
MOTS-c is a mitochondrial peptide on the FDA's 2026 review docket. The exercise-mimetic evidence, what the PCAC review decided, and the math.
Molecule guide · recovery
TB-500
TB-500 vs thymosin beta-4, the real state of the evidence, why it appears in doping sanctions, and the reconstitution math for typical vials.
Pillar · foundations
What Are Peptides?
Peptides explained plainly: the five things people mean by the word, which are approved drugs, whether they are safe or legal, and what works.
Foundations · reconstitution
Bacteriostatic Water
Bacteriostatic water for peptides: how it differs from sterile water, the 28-day rule after opening, storage, and how volume changes your math.
Pillar · weight loss
Peptides for Weight Loss
Weight-loss peptides ranked by evidence: approved GLP-1s that work, the next generation in trials, and the gray-market tier sold on hope.
Pillar · performance
Peptides for Muscle Growth
GH secretagogues raise hormones, not proven muscle. The honest evidence ranking, IGF-1 LR3 risks, WADA status, and what actually has data.
Molecule guide · GH axis
Ipamorelin
Ipamorelin raises growth hormone measurably; outcomes were never proven. The abandoned pharma history, FDA Category 2 status, and dosage math.
Molecule guide · GH axis
Sermorelin
Sermorelin is the only GH peptide with a real FDA approval in its past. What that legitimizes, the adult evidence gap, and nightly dosing math.
Molecule guide · GH axis
Tesamorelin
Tesamorelin is FDA-approved with real visceral-fat data, for HIV lipodystrophy. What the trials showed, off-label reality, cost, and dosing.
Guide · longevity
NAD+ Injections
NAD+ drips and shots examined: what declines with age, whether injected NAD+ reaches cells, how oral precursors compare, and what clinics charge.
Reference · GLP-1
GLP-1 Name Decoder
One molecule, two brands: the decoder table for every GLP-1 drug and brand name, answering all the 'are X and Y the same' questions at once.
Guide · practice
Peptide Stacking
The Wolverine stack, CJC/ipamorelin, GLP-1 add-ons: what stacking actually does, what no trial has ever tested, and the math and safety rules that change when vials multiply.
Guide · practice
Traveling With Peptides
Flying with peptides and GLP-1s: what TSA actually allows, how to keep vials cold in transit, why powder beats solution for travel, and the international borders that change everything.
Evidence report · GLP-1
Tirzepatide Before and After
Tirzepatide results without the marketing: 20.9% average loss in SURMOUNT-1, the month-by-month timeline, what happens on stopping, and how to read transformation photos skeptically.
Adjacent · longevity
Methylene Blue
Methylene blue is an approved drug, a lab dye, and a longevity trend at once. The mitochondrial rationale, the hormetic dosing curve, the serotonin-syndrome interaction that matters, and the grade problem.
Comparison · GH axis
Sermorelin vs Ipamorelin
Sermorelin and ipamorelin raise growth hormone through different receptors, and their 2026 difference is legal, not just pharmacological: one kept a compounding lane, the other is FDA Category 2.
Comparison · pipeline
Retatrutide vs CagriSema vs Survodutide
The three next-generation obesity drugs compared on actual trial data: retatrutide's 28.3% Phase 3 readout, CagriSema's 22.7% that disappointed, survodutide's liver angle, and realistic timelines.
Guide · GLP-1 practice
GLP-1 Microdosing
Half-dosing and microdosing GLP-1s: staying on 2.5 mg, splitting doses for cost or side effects, what the labels say, what evidence exists (little), and where the math gets dangerous.
Access · veterans
VA GLP-1 Coverage
VA coverage of GLP-1s in 2026, decoded: which diagnosis unlocks which drug, the MOVE! program requirement, non-formulary criteria for Wegovy and Zepbound, and the $5 to $11 copay reality.
Guide · GLP-1 practice
Switching Semaglutide to Tirzepatide
How the semaglutide-to-tirzepatide switch actually works: why there is no dose-conversion chart, the restart-at-2.5 logic, timing between last and first injections, and what to expect.
Pillar · longevity
Peptides for Longevity
The longevity peptide menu audited: epitalon's single-source telomere story, MOTS-c's preclinical promise, GHK-Cu, thymosins, NAD+ adjacents, and the twist: the one peptide class with actual mortality data.
Molecule guide · immune & airway
VIP Peptide
Vasoactive intestinal peptide (VIP) explained: the real physiology, the failed pharmaceutical history (aviptadil), the CIRS/mold-illness nasal-spray protocols, and what compounded VIP actually rests on.
Comparison · GH axis
GHRP-2 vs Ipamorelin
GHRP-2 and ipamorelin hit the same receptor with different manners: stronger GH pulse with hunger and cortisol on one side, cleaner selectivity on the other. Neither has outcomes or a legal lane.
Comparison · sexual health
PT-141 vs Kisspeptin vs Oxytocin
The three peptides sold for desire and connection, compared honestly: PT-141's approved pedigree, kisspeptin's fascinating trials, oxytocin's collapsed hype, and what evidence supports each.
Guide · GLP-1 practice
When Do GLP-1s Start Working?
How long semaglutide and tirzepatide take to suppress appetite and move the scale: first-injection effects, the escalation reality, week-by-week expectations, and when 'not working' is real.
Cost & access · GLP-1
Zepbound Cost
Zepbound's real price map: list price near $1,060, the LillyDirect self-pay vials from $349, savings-card mechanics for the insured, pharmacy variations, and the compounded question after the shortage.
Data reference · free to cite · updated monthly
Peptide Statistics
The peptide boom in numbers: search demand, GLP-1 usage, trial results, real monthly prices, and gray-market safety data, each with a primary source.
The retatrutide hub
The next-generation GLP-1 gets its own section: