Peptivoice

Semax reconstitution calculator

ACTH(4-10) analog · nootropic

Semax is a synthetic fragment of ACTH developed in Russia, where it holds actual drug approval for neurological indications and is commonly used as a nasal spray. In the US it circulates as a research chemical prized by the nootropics community - with the entire Russian clinical literature and none of the FDA oversight.

Regulatory status (August 2026). Not FDA-approved and never reviewed by the FDA. Approved and prescribed in Russia (stroke recovery, cognitive indications) - a regulatory history that does not transfer to the US, where it is sold as a research chemical.
Reconstitution · Semaxmath only - no dosing advice
0102030405060708090100U-100 · UNITS

Enter vial size, water volume, and the dose your provider gave you.

This tool converts the numbers you enter (dose ÷ concentration = volume). It never suggests a dose. The FDA has documented hospitalizations caused by mg / ml / unit conversion errors with vial-and-syringe products - if the readout surprises you, stop and verify with your prescriber or pharmacist.

Questions people actually search

Is Semax legal in the US?

It's not a controlled substance, so possession isn't criminalized - but it is not FDA-approved, cannot be legally sold for human use, and its Russian approval carries zero regulatory weight in the US system.

Is Semax taken nasally or injected?

In Russian clinical practice, Semax is a nasal spray - the approved route. Gray-market vials in the US are often reconstituted for either nasal or subcutaneous use. The math is identical (concentration × volume); the absorption and the evidence base are not.

What does the research actually show?

Russian trials report benefits in stroke recovery and cognitive performance, but most are small, older, and published outside Western peer review. Independent Western replication is essentially absent - the honest label is 'interesting, unverified elsewhere'.

Read the full reconstitution guide →