Semaglutide reconstitution calculator
the API in Ozempic® / Wegovy®
Semaglutide is a GLP-1 receptor agonist approved by the FDA in pen form. Vial-and-syringe use exists mainly through compounding pharmacies, where the FDA has documented hospitalizations caused by mg/ml/unit conversion errors - exactly the math this calculator makes explicit.
Enter vial size, water volume, and the dose your provider gave you.
This tool converts the numbers you enter (dose ÷ concentration = volume). It never suggests a dose. The FDA has documented hospitalizations caused by mg / ml / unit conversion errors with vial-and-syringe products - if the readout surprises you, stop and verify with your prescriber or pharmacist.
Questions people actually search
How many units is 0.25 mg of semaglutide?
It depends entirely on the vial concentration. In a 5 mg vial reconstituted with 2 ml (2.5 mg/ml), 0.25 mg is 0.1 ml = 10 units. In a 2.5 mg/ml prefilled compounded vial the same holds, but concentrations vary by pharmacy - always compute from the actual mg and ml on your label.
Why did the FDA warn about semaglutide dosing errors?
The FDA documented reports of patients drawing 5 to 20 times the intended dose from compounded vials, usually by confusing units, ml, and mg. Several required medical attention. A written conversion - dose ÷ concentration = volume - prevents this class of error.
Is compounded semaglutide still legal?
Routine compounding of semaglutide is restricted now that the branded shortage has been resolved; limited exceptions exist. State rules and enforcement vary, and Novo Nordisk has litigated against sellers. The branded pens remain the only FDA-approved forms.