Peptivoice

PT-141 reconstitution calculator

bremelanotide - approved as Vyleesi®

PT-141 (bremelanotide) is a melanocortin-receptor agonist - one of the few gray-market peptides with an actual FDA-approved sibling. The approved product is a fixed-dose autoinjector; vial forms circulate through men's clinics and research sellers, where the conversion math (and the blood-pressure contraindications) get lost.

Regulatory status (August 2026). Bremelanotide is FDA-approved as Vyleesi (a prefilled autoinjector) for hypoactive sexual desire disorder in premenopausal women. Compounded and research-chemical PT-141 vials are not approved forms, and the melanocortin class carries blood-pressure warnings.
Reconstitution · PT-141math only - no dosing advice
0102030405060708090100U-100 · UNITS

Enter vial size, water volume, and the dose your provider gave you.

This tool converts the numbers you enter (dose ÷ concentration = volume). It never suggests a dose. The FDA has documented hospitalizations caused by mg / ml / unit conversion errors with vial-and-syringe products - if the readout surprises you, stop and verify with your prescriber or pharmacist.

Questions people actually search

Is PT-141 the same as Vyleesi?

Same molecule (bremelanotide), different products. Vyleesi is an FDA-approved fixed-dose (1.75 mg) autoinjector for premenopausal women with HSDD. Vial-form PT-141 sold online or compounded for other uses is not an approved product.

How many units is 1 mg of PT-141?

From a 10 mg vial reconstituted with 2 ml (5 mg/ml), 1 mg = 0.2 ml = 20 units. With 3 ml of water (3.33 mg/ml) the same 1 mg is 30 units. Compute from your actual vial and water volume - never copy someone else's unit count.

What should I know about PT-141 safety?

The approved label for bremelanotide carries warnings about transient blood-pressure increases (it is not recommended for people with uncontrolled hypertension or cardiovascular disease), plus common nausea and flushing. Those warnings apply to the molecule, not just the brand.

Read the full reconstitution guide →