MOTS-c reconstitution calculator
mitochondrial-derived peptide
MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA, studied as an exercise-mimetic and metabolic regulator. Human data is limited to small studies; most evidence is preclinical. It sits on the FDA's 2026 review docket, which is why searches for it spiked.
Enter vial size, water volume, and the dose your provider gave you.
This tool converts the numbers you enter (dose ÷ concentration = volume). It never suggests a dose. The FDA has documented hospitalizations caused by mg / ml / unit conversion errors with vial-and-syringe products - if the readout surprises you, stop and verify with your prescriber or pharmacist.
Questions people actually search
What is MOTS-c studied for?
Published research - mostly in animals and cells - examines insulin sensitivity, exercise capacity, and metabolic regulation. A small number of early human studies exist. No efficacy claim has been evaluated by the FDA.
Did the FDA approve MOTS-c in 2026?
No. MOTS-c was among peptides reviewed by the FDA's Pharmacy Compounding Advisory Committee in July 2026. Committee recommendations are consultative; as of August 2026 no reclassification has been enacted and no legal compounding pathway exists.
How many units is 5 mg of MOTS-c?
From a 10 mg vial with 2 ml of water (5 mg/ml), 5 mg = 1 ml = 100 units - a full large insulin syringe. With 4 ml of water it would be 2 ml, exceeding any insulin syringe, which the calculator flags. Water volume decides how practical a draw is.